General Information

Product

IRAKM Antibody

Description

Affinity Purified Interleukin-1 receptor-associated kinase 3 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 450-500 on mouse Interleukin-1 receptor-associated kinase 3 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polylclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

Q9Y616

Overview

Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.

Molecular Function

ATP binding

magnesium ion binding

protein heterodimerization activity

protein homodimerization activity

protein serine/threonine kinase activity

Subcellular Location

Nucleus, Cytoplasm

Expression

Expressed predominantly in peripheral blood lymphocytes.

Structure

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.

Alternative Nomenclature

ASRT5 antibody

IL 1 receptor associated kinase M antibody

Interleukin 1 receptor associated kinase 3 antibody

Interleukin 1 receptor associated kinase M antibody

IRAK M antibody

IRAK-3 antibody

IRAK-M antibody

Irak3 antibody