General Information

Product

ROR1 Antibody

Description

Affinity Purified Receptor tyrosine kinase-like orphan receptor 1Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide correspondingto C terminalamino acids 900-918 on Human ROR1 protein. Peptide was coupled to a carrier protein using heterobifunctional cross linker.

Sequence:

TVKGNKSQKPYKIDSKQAS

Accession #

GenBank: EAX06557.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

UPI0000EE3178

Overview

Tyrosine-protein kinase receptor whose role is not yet clear.

Molecular Function

ATP binding; transmembrane receptor protein Tyrosine kinase activity; Wnt-protein binding

Subcellular Location

Membrane; Single-pass type I membrane protein

Expression

Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm.

Structure

Contains 1 FZ (frizzled) domain; Contains 1 Ig-like C2-type (immunoglobulin-like) domain; Contains 1 Kringle domain; Contains 1 Protein kinase domain

Alternative Nomenclature

dJ537F10.1 antibody

MGC99659 antibody

Neurotrophic tyrosine kinase antibody

Receptor tyrosine kinase like orphan receptor 1 antibody

receptor-related 1 antibody

RGD1559469 antibody

RP11 24J23.1 antibody

Tyrosine kinase like orphan receptor 1 antibody