General Information

Product

MAP3K4 Antibody

Description

Affinity Purified Mitogen-activated protein kinase kinase kinase 4 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1558-1608 on human MAP3K4 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9Y6R4

Overview

Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6.

Molecular Function

Kinase, Serine/threonine-protein kinase, Transferase

Subcellular Location

Cytoplasm > perinuclear region

Expression

Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues.

Structure

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. Contains 1 protein kinase domain.

Alternative Nomenclature

dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4) antibody

FLJ42439 antibody

KIAA0213 antibody

MAP three kinase 1 antibody

MAP/ERK kinase kinase 4 antibody

MAP3K4 antibody

MAPKKK4 antibody

MEK kinase 4 antibody

MEKK4 antibody

Mitogen-activated protein kinase kinase kinase 4 antibody

MTK1 antibody

predicted protein of HQ0412 antibody

PRO0412 antibody

RP3-473J16.4 antibody

SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of antibody