General Information

Product

VKORC1 Antibody

Description

Vitamin K epoxide reductase complex subunit 1 Antibody

Verified Applications

ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 10-60 on human VKORC1 protein.

Accession #

GenBank: AJE63371.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.70 µg/µl in antibody stabilization buffer

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

DB

1:50,000

ELISA

1:50,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q6TEK4

Overview

Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development.

Molecular Function

Oxidoreductase, Quinone binding, vitamin-K-epoxide reductase

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein

Expression

Highly expressed in liver. Detected at lower levels in lung, kidney and testis.

Alternative Nomenclature

3-epoxide reductase subunit 1 antibody

EDTP308 antibody

FLJ00289 antibody

IMAGE3455200 antibody

MGC2694 antibody

MST134 antibody

MST576 antibody

Phylloquinone epoxide reductase antibody

Vitamin K dependent clotting factors deficiency 2 antibody

Vitamin K epoxide reductase complex subunit 1 antibody

Vitamin K1 2 antibody

Vitamin K1 epoxide reductase (warfarin sensitive) antibody

VKCFD2 antibody

VKOR antibody

VKORC1 antibody