General Information

Product

IQSEC3 Antibody

Description

Affinity Purified IQ motif and SEC7 domain-containing protein 3 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1100-1150 on human IQ motif and SEC7 domain-containing protein 3.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunohistochemistry

1:150

Western Blot

1:500

Protein

Uniprot #

Q9UPP2

Overview

Acts as a guanine nucleotide exchange factor (GEF) for ARF1.

Molecular Function

ARF guanyl-nucleotide exchange factor activity

Subcellular Location

Cytoplasm

Expression

Expressed specifically in the adult brain, predominantly in the cerebral cortex and the olfactory bulb, but not in the fetal brain. Expressed only in mature neurons, but not in undifferentiated neural stem precursor cells (NSPCs), nor in glioma cells.

Structure

Coiled coil

Alternative Nomenclature

IQ motif and Sec7 domain 3 antibody

IQ motif and SEC7 domain-containing protein 3 antibody

Iqsec3 antibody

KIAA1110 antibody

MGC30156 antibody