General Information

Product

FGD3 Antibody

Description

Affinity Purified Faciogenital dysplasia 3 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-320 on human FYVE, RhoGEF and PH domain-containing protein 3.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

Q5JSP0

Overview

Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.

Molecular Function

guanyl-nucleotide exchange factor activity

metal ion binding

Rho guanyl-nucleotide exchange factor activity

small GTPase binding

Subcellular Location

Cytoplasm

Structure

Repeat, Zinc-finger

Alternative Nomenclature

Faciogenital dysplasia 3 antibody

FGD1 family, member 3 antibody

FGD3 antibody

FYVE antibody

FYVE, RhoGEF and PH domain containing 3 antibody

ZFYVE5 antibody

Zinc finger FYVE domain containing protein 5 antibody