General Information

Product

GPCR GPR7 Antibody

Description

Affinity Purified Neuropeptides B/W receptor type 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human neuropeptides B/W receptor type 1 protein.

Accession #

NCBI: NP_005276

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P48145

Overview

Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.

Molecular Function

G-protein coupled receptor, Receptor, Transducer.

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Expression

Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.

Structure

Belongs to the G-protein coupled receptor 1 family.

Alternative Nomenclature

G protein coupled receptor 7GPR7MGC129755Neuropeptides B and W receptor 1NPB and NPW receptor 1NPBWR1opioid somatostatin like receptor 7