General Information

Product

Affinity Purified TPCN1 Antibody

Description

Two pore calcium channel protein 1 isoform 2 Antibody Affinity Purified

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within TMD7 and TMD8 on human TPC1 protein.

Accession #

NCBI: NP_060371.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9ULQ1

Overview

Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca2+ channels (VDCC) across the lysosomal and endosomal membrane.

Molecular Function

Calcium channel, Ion channel, Voltage-gated channel

Subcellular Location

Lysosome membrane; Multi-pass membrane protein, Endosome membrane; Multi-pass membrane protein

Expression

Highest expression found in the heart and kidney, and lowest expression found in the spleen.

Structure

Dimer.

Alternative Nomenclature

TPC1 antibody

TPCN 1 antibody

Two pore calcium channel protein 1 antibody

Two pore channel 1 antibody

Two pore segment channel 1 antibody

Voltage dependent calcium channel protein TPC1 antibody