General Information

Product

PAR2 Antibody

Description

Affinity Purified Proteinase-activated receptor 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Chimpanzee, Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 300-370 of mousePAR2.

Accession #

NCBI: NP_032000.3

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.62 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:15,00-1:20,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:250

Protein

Uniprot #

P55086

Overview

Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.

Structure

Interacts with TLR4, COPS5 and TMED2. Also interacts with GNAQ, GNA11, GNA12, GNA13, and GNA14.

Alternative Nomenclature

Coagulation factor II receptor like 1

Coagulation factor II thrombin receptor like 1

F2RL1

G protein coupled receptor 11

GPR11

PAR 2

Proteinase activated receptor 2

Thrombin receptor like 1