General Information

Product

Epac1 Antibody

Description

Affinity Purified Rap Guanine Nucleotide Exchange Factor 3 Antibody N-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Horse, Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to amino acid region 9-26 of Epac1, peptide was covalently modified.

Synthetic peptide:

PRSCSYQLLLEHQRPSCI

Accession #

GenBank: AAD12740.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.59µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Western Blot

1:500

Protein

Uniprot #

O95398

Overview

Guanine nucleotide exchange factor for RAP1A and RAP2A small GTPases that are activated by binding cAMP

Molecular Function

cAMP-binding; Nucleotide-binding

Subcellular Location

Endomembrane system

Expression

Widely expressed with highest levels in kidney, heart, thyroid and brain

Structure

Interacts with PDE3B

Alternative Nomenclature

bcm910 antibody

CGEF 1 antibody

Epac 1 antibody

EPAC antibody

Exchange protein directly activated by cAMP 1 antibody

MGC21410 antibody

RAP guanine nucleotide exchange factor antibody

RAPGEF3 antibody