General Information

Product

ITK Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 550-600 onhuman ITK protein.

Accession #

GenBank: BAA02873.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.54-0.57 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q08881

Overview

Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells.

Molecular Function

ATP binding, metal ion binding, non-membrane spanning protein tyrosine kinase activity

Subcellular Location

Cytoplasm (Note: Localizes in vicinity of cell surface receptors in plasma membrane after receptor stimulation)

Expression

T-cell lines and natural killer cell lines.

Alternative Nomenclature

EMT antibody

Homolog of mouse T cell itk/tsk antibody

IL 2 inducible T cell kinase antibody

Itk antibody

Kinase EMT antibody

LPFS1 antibody

LYK antibody

MGC126257 antibody

MGC126258 antibody

PSCTK 2 antibody

T cell specific kinase antibody

TSK antibody

Tyrosine protein kinase antibody

Tyrosine protein kinase ITK/TSK antibody