General Information

Product

TGM1 Antibody

Description

Affinity Purified Coagulation factor XIII A chain Antibody C-epitope

Verified Applications

CM, ELISA, ICC, IHC, IF, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on Coagulation factor XIIIA chain precursor

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61-0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

Dot Blot

1:30,000

ELISA

1:30,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Western Blot

1:450

Protein

Uniprot #

Q8BH61

Overview

Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.

Molecular Function

metal ion binding, protein-glutamine gamma-glutamyltransferase activity

Subcellular Location

Cytoplasm, Secreted

Structure

Tetramer of two A chains and two B chains

Alternative Nomenclature

ARCI1 antibody

Epidermal TGase antibody

ICR2 antibody

KTG antibody

LI antibody

LI1 antibody

Protein glutamine gamma glutamyltransferase K antibody

TG(K) antibody

TGase 1 antibody

TGASE antibody

TGase K antibody

TGK antibody

TGM1 antibody

Transglutaminase 1 (K polypeptide epidermal type I, protein glutamine gamma glutamyltransferase) antibody

Transglutaminase 1 antibody

Transglutaminase K antibody