General Information

Product

PrLZ / TPD52 Antibody

Description

Affinity Purified Prostate leucine zipper isoform 5 Antibody C-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 101-151 on human Prostate leucine zipper isoform 5 protein.

Accession #

NCBI: NP_001020423.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.69 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500-1:1,000

Protein

Uniprot #

P55327

Molecular Function

calcium ion binding, protein heterodimerization activity, protein homodimerization activity

Subcellular Location

cytoplasm, perinuclear region of cytoplasm, endoplasmic reticulum

Expression

Isoform 2 is expressed in colon, breast, prostate, pancreas and kidney tumor cell lines. Isoform 2 is expressed at high levels in kidney, prostate, brain, small intestine and pancreas, at moderate levels in placenta and colon, at low levels in lung, liver and at very low levels in spleen, thymus, peripheral mononuclear blood cells, testis and ovary.

Structure

Forms a homodimer or heterodimer with other members of the family. All isoforms interact with several 14-3-3 proteins.

Alternative Nomenclature

D52 antibody

Human 19.8 kDa protein mRNA, complete cds antibody

N8L antibody

PC 1 antibody

PC1/MRPS28 fusion protein antibody

PrLZ antibody

Prostate and colon associated protein antibody

Prostate leucine zipper antibody

Protein N8 antibody

TPD52 antibody

Tumor protein D52 antibody