General Information

Product

Podoplanin Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse

Immunogen

Synthetic peptide taken within amino acid region 80-130 on human Podoplanin protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q86YL7

Overview

Invovled in cell migration and actin cytoskeleton organization. Induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion when expressed in keratinocytes.

Molecular Function

Sialic acid; cell shape; developmental protein

Subcellular Location

Cell membrane; Cell projection

Expression

Placenta, lung, skeletal muscle and brain. Weakly expressed in brain kidney and liver.

Structure

Belongs to podoplanin family

Alternative Nomenclature

AGGRUS antibody

GLYCOPROTEIN 36 KD antibody

gp 36 antibody

GP 38 antibody

GP 40 antibody

HT1A1 antibody

hT1alpha1 antibody

hT1alpha2 antibody

Lung type I cell membrane associated glycoprotein T1A 2 antibody

OTS 8 antibody

PA2.26 antigen antibody

Podoplanin antibody

PSEC0003 antibody

PSEC0025 antibody

T1 ALPHA GENE antibody

T1A 2 antibody

T1A antibody