General Information

Product

TLR1 Antibody

Description

Affinity Purified Toll-like receptor 1Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Predicted: Human

Immunogen

Synthetic peptide taken within amino acid region 200-250 on mouse toll-like receptor 1 protein.

Accession #

NCBI: NP_109607.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.67 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:20,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9EPQ1

Overview

Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.

Molecular Function

Receptor, Transmembrane signaling receptor activity, triacyl lipopeptide binding

Subcellular Location

Cell membrane; Single-pass type I membrane protein, Cytoplasmic vesicle > phagosome membrane; Single-pass type I membrane protein

Structure

Binds MYD88 (via TIR domains) (By similarity). Interacts (via extracellular domain) with TLR2. Ligand binding induces the formation of a heterodimer with TLR2 (By similarity). Interacts with CNPY3.

Alternative Nomenclature

CD281 antibody

KIAA0012 antibody

LPRS5 antibody

rsc786 antibody

Similar to Drosophila Toll protein antibody

TIL antibody

TIL. LPRS5 antibody

Tlr1 antibody

Toll (Drosophila) homolog antibody

Toll like receptor 1 antibody

Toll/Interleukin 1 receptor like antibody