General Information

Product

PDE3B Antibody

Description

Affinity Purified cGMP-inhibited 3",5"-cyclic phosphodiesterase B Antibody

Verified Applications

CM, ELISA, ICC, IHC, IP, WB

Host

Goat

Species Cross Reactivity

Chicken, Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1060-1110 on human PDE3B protein.

Accession #

Gen Bank: BAA09306

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:500

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:500

Immunofluorescence

1:500

Immunohistochemistry

1:500

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q13370

Overview

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3.

Molecular Function

Hydrolase, 3",5"-cyclic-AMP phosphodiesterase activity, cAMP binding

Subcellular Location

Membrane; Multipass membrane protein

Expression

Abundant in adipose tissues.

Structure

Interacts with PIK3CG. Interacts with RAPGEF3 and PIK3R6 (By similarity).

Alternative Nomenclature

5""-cyclic phosphodiesterase B antibody

adipocyte cAMP phosphodiesterase cGMP inhibited antibody

AI847709 antibody

cAMP Phosphodiesterase, adipocyte, cGMP-inhibited antibody

CGIP1 antibody

CGIPDE B antibody

cGMP inhibited 3 5 cyclic phosphodiesterase B antibody

CGMP inhibited cAMP phophodiesterase antibody

cGMP-inhibited 3"" antibody

Cyclic GMP-inhibited phosphodiesterase B antibody

Cyclic nucleotide phosphodiesterase antibody

HcGIP1 antibody

Phosphodiesterase 3B cGMP inhibited antibody