General Information

Product

IFI27 Antibody

Description

Affinity Purified Interferon, alpha-inducible protein 27Antibody N-epitope

Verified Applications

ELISA, ICC/IF, IHC-Fr, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide: multiple antigenic peptide (8 branch) corresponding to amino acids 2-13 of Human IFI27.

Sequence:

EASALTSSAVTS

Accession #

NCBI: NP_005523.3

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:100,000

ELISA

1:100,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

UPI000019A7CD

Overview

Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9.

Molecular Function

Lamin binding; RNA polymerase II activating transcription factor binding

Subcellular Location

Mitochondrion; Multi-pass membrane protein

Expression

Up-regulated by interferons

Structure

Belongs to the IFI6/IFI27 family.

Alternative Nomenclature

2310061N23Rik antibody

FAM14D antibody

IFI 27 antibody

Interferon alpha induced 11.5 kDa protein antibody

Interferon inducible protein 27 antibody

interferon-stimulated gene 12 antibody

ISG 12 antibody

ISG12A antibody

P27 antibody