General Information

Product

Cytokeratin 7 Antibody

Description

keratin, type II cytoskeletal 7 Antibody Affinity PurifiedC-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region419-469 on human keratin, type II cytoskeletal 7 protein.

Accession #

NCBI: NP_005547

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P08729.5

Overview

Serves to block interferon-dependent interphase and stimulates DNA synthesis. Plays a role in the translational regulation of human papillomavirus type 16 E7 mRNA.

Molecular Function

Structural molelcule activity; Host-virus interaction

Subcellular Location

Cytoplasm

Expression

Expressed in cultured epidermal, bronchial and mesothelial cells. Seen throughout the glandular cells at the junction of the stomac and esophagus; not present in the esophogus, colon, ectocervix and liver.

Structure

Heterotetramer of two type I and two type II keratins, interacts with eukaryotic translation initiator factor 3 subunit EIF3S10, HPV16 E7, and GPER1.

Alternative Nomenclature

CK 7 antibody

Cytokeratin 7 antibody

K2C7 antibody

K7 antibody

Keratin 55k type ii cytoskeletal antibody

Keratin 7 antibody

KRT 7 antibody

Krt2-7 antibody

Sarcolectin antibody

SCL antibody

Type-II keratin Kb7 antibody