General Information

Product

LYK5 Antibody

Description

Affinity Purified STE20-related kinase adapter protein alpha Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 381-431 on human STE-20 related kinase adapter protein alpha.

Accession #

NCBI: NP_001003787.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q7RTN6

Overview

Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

Molecular Function

ATP Binding, protein kinase activator activity, kinase binding, transferase activity, transferring phosphorus-containing groups

Subcellular Location

Nucleus, cytoplasm

Expression

Expressed in liver

Structure

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

Contains 1 protein kinase domain.

Alternative Nomenclature

Protein kinase LYK5 antibody

Serologically defined breast cancer antigen NY BR 96 antibody

STE20 related adapter protein antibody

STRAD alpha antibody

STRAD antibody