General Information

Product

IL17A Antibody

Description

Affinity Purified Interleukin-17AAntibody

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 110-150 on human Interleukin-17A precursor protein.

Accession #

NCBI: NP_002181

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.95 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Western Blot

1:500

Protein

Uniprot #

Q96F46

Overview

Receptor for IL17A, IL17F and, in dimer with IL17RE, for IL17C. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.

Molecular Function

interleukin-17 receptor activity

Subcellular Location

Isoform 1: membrane, single-pass type I membrane protein; Isoform 2: secreted

Expression

Widely expressed.

Alternative Nomenclature

CTLA 8 antibody

Cytotoxic T lymphocyte associated serine esterase 8 antibody

IL-17A antibody

IL17 antibody

Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody

Interleukin 17A antibody

OTTHUMP00000016597 antibody

OTTMUSP00000046003 antibody