General Information

Product

Cytokeratin 7 Antibody

Description

keratin, type II cytoskeletal 7 Antibody

Verified Applications

ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 10-60 on human keratin, type II cytoskeletal 7 protein.

Accession #

NCBI:  NP_005547

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:250

Protein

Uniprot #

P08729.5

Overview

Serves to block interferon-dependent interphase and stimulates DNA synthesis.  Plays a role in the translational regulation of human papillomavirus type 16 E7 mRNA.

Molecular Function

Structural molelcule activity; Host-virus interaction

Subcellular Location

Cytoplasm

Expression

Expressed in cultured epidermal, bronchial and mesothelial cells.  Seen throughout the glandular cells at the junction of the stomac and esophagus; not present in the esophogus, colon, ectocervix and liver.

Structure

Heterotetramer of two type I and two type II keratins, interacts with eukaryotic translation initiator factor 3 subunit EIF3S10 , HPV16 E7, and GPER1.

Alternative Nomenclature

CK 7 antibody

Cytokeratin 7 antibody

D15Wsu77e antibody

K2C7 antibody

K7 antibody

Keratin 55k type ii cytoskeletal antibody

Keratin 7 antibody

Keratin simple epithelial type 1 k7 antibody

Keratin type II cytoskeletal 7 antibody

Keratin-7 antibody

KRT 7 antibody

Krt2-7 antibody

MGC11625 antibody

MGC129731 antibody

mgc3625 antibody

Sarcolectin antibody

SCL antibody

Type ii mesothelial keratin k7 antibody

Type-II keratin Kb7 antibody