General Information

Product

GTP cyclohydrolase 1 Antibody Affinity Purified

Description

Affinity Purified GTP cyclohydrolase 1 Antibody N-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

N-epitope synthetic peptide taken within amino acid region 1-50 on GTPCHI protein.

Accession #

GeneBank: AAH05643

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-0.98 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000

ELISA

1:20,000

Western Blot

1:500-1:750

Protein

Uniprot #

Q05915

Overview

Positively regulates nitric oxide synthesis in endothelial cells. Invovled in dopamine synthesis and pain sensitivity and persistence.

Molecular Function

Cofactor biosynthesis; GTP binding; Coenzyme binding; Calcium ion binding

Subcellular Location

Cytoplasm; Nucleus

Structure

Toroid-shaped homodecamer. Composed of two pentamers of five dimers.

Alternative Nomenclature

dystonia 14 antibody

DYT 5 antibody

DYT14 antibody

DYT5a antibody

GCH antibody

GTP CH 1 antibody

GTP cyclohydrolase 1 (dopa responsive dystonia) antibody

Guanosine 5" triphosphate cyclohydrolase I antibody

HPABH4B antibody