General Information

Product

CXCR2 Antibody

Verified Applications

CM, ELISA, ICC/IF, IHC-Fr, IHC-P, IP, FC, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide:

EDLSNYSYSSTLPPFLLDAAPC

Corresponding to amino acids 18-39 of Human CXCR2.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

~.50µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:250

Western Blot

1:500 Predicted molecular weight: 55 kDa

Protein

Uniprot #

P25025

Overview

Receptor for interleukin-8, binding of IL-8 to the receptor causes the activation of neutrophils. This response is mediated by a G-protein which activates a phosphatidyinositol-calcium second messenger system.

Molecular Function

G-Protein coupled receptor, Transducer, chemokine receptor activity

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Up-regulated by CREB3

Structure

Binds to HIV-1 Tat and interacts with ARRB1

Alternative Nomenclature

C-X-C chemokine receptor type 2 antibody

CD 182 antibody

CD182 antigen antibody

CDw128b antibody

Chemokine (CXC) receptor 2 antibody

CMKAR2 antibody

CXCR2 antibody

GRO/MGSA receptor antibody

High affinity interleukin-8 receptor B antibody

IL8R B antibody

IL8R2 antibody

IL8RA antibody

Interleukin 8 receptor, beta antibody

Interleukin 8 receptor, type 2 antibody