General Information

Product

CXCR1 Antibody

Description

Affinity Purified CXCR1 Antibody N-epitope

Verified Applications

ELISA, IHC-P, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide derived from the N terminus of Human CXCR1 protein.

Accession #

GenBank: AAY21523

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

.50µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:250

Western Blot

1:500. Predicted molecular weight: 40 kDa.

Protein

Uniprot #

P25024

Overview

Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.

Molecular Function

Chemotaxis

Subcellular Location

Cell membrane; Multi-pass membrane protein

Structure

Belongs to the G-protein coupled receptor 1 family

Alternative Nomenclature

C C antibody

C C CKR 1 antibody

C-X-C chemokine receptor type 1 antibody

CCCKR1 antibody

CD 181 antibody

CD128 antibody

CKR 1 antibody

CMKAR1 antibody

CXC-R1 antibody

High affinity interleukin-8 receptor A antibody

IL 8 receptor type 1 antibody

IL 8R A antibody