General Information

Product

ARHGEF7 Antibody

Description

Affinity Purified Rho-guanine nucleotide exchange factor 7 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 595-805 on human ARHGEF7 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q14155

Overview

Acts as RAC1 guanine nucleotide exchange factor and can induce membrane ruffling.

Molecular Function

Neurogenesis

Subcellular Location

Cell junction; foacl adhesion; Cell projection ruffle; Cell cortex

Structure

Interacts with PAK kinases through SH3 domain. Interacts with GIT1 and TGFB1I1. Interacts with PTK2/FAK1 and RAC1.

Alternative Nomenclature

ARHG7 antibody

Beta pix antibody

COOL1 antibody

Nbla10314 antibody

P50 antibody

p85 antibody

P85SPR antibody

PAK interacting exchange factor beta antibody

PAK3 antibody

SH3 domain containing proline rich protein antibody