Product | Pan PDE5A Antibody |
Description | cGMP-specific 3,5-cyclic phosphodiesterase isoform 1 Antibody |
Verified Applications | CM, ELISA, ICC, IF, IHC, IP, WB |
Host | Rabbit |
Species Cross Reactivity | Chicken, Human |
Immunogen | Recombinant protein common to all PDE5A variants corresponding to human PDE5A protein. |
Accession # | NCBI: NP_001074 |
Physical Properties | |
Quantity | 100 µg |
Volume | 200 µl |
Concentration | 0.55µg/µl in antibody stabilization buffer |
Immunoglobulin | IgG |
Clonality | Polyclonal |
Storage | -20⁰C for long term storage |
Application Protocol | |
Confocal Microscopy | 1:250 |
DB | 1:10,000 |
ELISA | 1:10,000 |
Immunocytochemistry | 1:250 |
Immunofluorescence | 1:250 |
Immunohistochemistry | 1:250 |
Immunoprecipitation | 1:250 |
Western Blot | 1:500-1:1,000 |
Protein | |
Uniprot # | O76074 |
Overview | Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5-GMP. |
Molecular Function | Hydrolase, 3,5-cyclic-GMP phosphodiesterase activity, cGMP binding |
Subcellular Location | cytosol |
Expression | Expressed in aortic smooth muscle cells, heart, placenta, skeletal muscle and pancreas and, to a much lesser extent, in brain, liver and lung. |
Alternative Nomenclature | 5-cyclic phosphodiesterase antibody CGB PDE antibody cGMP binding cGMP specific 3 5 cyclic nucleotide phosphodiesterase antibody cGMP binding/cGMP specific phosphodiesterase antibody cGMP specific phosphodiesterase PDE5A antibody cGMP specific phosphodiesterase type 5A antibody cGMP-specific 3 antibody CN5A antibody CN5N antibody PDE 5 antibody PDE 5A antibody PDE5A antibody Phosphodiesterase 5A antibody Phosphodiesterase 5A cGMP specific antibody Phosphodiesterase isozyme 5 antibody |
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