General Information

Product

Factor VIII Antibody

Description

Affinity Purified coagulation factor VIII Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 200-250 on human Coagulation Factor VIII protein.

Accession #

GenBank: CBL59398.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-0.95 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

D5H408

Overview

Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.

Molecular Function

Copper ion binding; oxidoreductase activity

Subcellular Location

Secreted > extracellular space

Structure

Interacts with vWF. vWF binding is essential for the stabilization of F8 in circulation.

Alternative Nomenclature

AHF antibody

Antihemophilic factor antibody

Coagulation factor VIII antibody

coagulation factor VIII, procoagulant component antibody

DXS1253E antibody

F8 antibody

F8b antibody

F8c antibody

factor VIII F8B antibody

Factor VIIIa light chain antibody

FactorVIII antibody

FVIII antibody

Hema antibody

Hemophilia A antibodyProcoagulant component antibody