General Information

Product

CACNB2 Antibody Affinity Purified

Description

Affinity Purified Voltage dependent L-type calcium channel subunit beta-2 Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 500-600 on rat voltage-dependent L-type calcium channel subunit beta-2 protein

Accession #

NCBI: NP_446303

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.6 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q8VGC3

Overview

The beta subunit of voltage-dependent calcium channel which contributes to calcium channel function by increasing peak calcium current, shifting the voltage dependencies fo activation and inactivation, modulating G-protein inhibition and controllin the alpha-1 subunit membrane targeting.

Molecular Function

Calcium; Transport; Ion transport

Subcellular Location

Cell membrane; Sacrolemma; Peripheral membrane protein, cytoplasmic side

Expression

Heart and brain. Lower expression in lung.

Structure

L-type channel is composed of four subunits: alpha-1, alpha-2, beta and gamma.

Alternative Nomenclature

AW060387 antibody

Ca(V) beta 2 antibody

CAB2 antibody

CAVB2 antibody

Cavbeta2 antibody

Cchb2 antibody

Lambert Eaton Myasthenic syndrome antigen antibody

MYSB antibody