General Information

Product

CCR6 Antibody

Description

Affinity Purified C-C chemokine receptor type 6 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human C-C chemokine receptor type 6 protein.

Accession #

NCBI: NP_004358.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:250

Western Blot

1:500

Protein

Uniprot #

P51684

Overview

Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.

Molecular Function

G-protein coupled receptor; Transducer; C-C chemokine receptor activity

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes.

Structure

Belongs to the G-protein coupled receptor 1 family.

Alternative Nomenclature

BN 1 antibody

C C chemokine receptor type 6 antibody

CCR-6 antibody

CD196 antibody

Chemokine (C C motif) receptor 6 antibody

CKR 6 antibody

DRY6 antibody

G protein coupled receptor 29 antibody

GPR-CY4 antibody

LARC receptor antibody

Seven transmembrane receptor lymphocyte 22 antibody

STRL22 antibody